- Abstract:
-
Recent work has shown that a major population of murine influenza A specific cytotoxic T lymphocytes (CTL) recognize the viral nucleoprotein. In order to investigate the mechanism by which this nonglycoprotein component of the virus is recognized by CTL, a series of deletion mutants of an A virus NP gene were studied. The results showed that CTL recognize three distinct epitopes of the NP molecule. Both N- and C-terminal fragments of the protein are transported, independently of each other, t...
Expand abstract - Publisher copy:
- 10.1016/0092-8674(85)90103-5
-
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- Journal:
- Cell
- Volume:
- 42
- Issue:
- 2
- Pages:
- 457-467
- Publication date:
- 1985-09-05
- DOI:
- EISSN:
-
1097-4172
- ISSN:
-
0092-8674
- URN:
-
uuid:1f5a3acb-2bf3-472a-8e12-1f6ac06b8a33
- Source identifiers:
-
95901
- Local pid:
- pubs:95901
- Language:
- English
- Keywords:
- Copyright date:
- 1985
Journal article
Cytotoxic T cells recognize fragments of the influenza nucleoprotein.
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