Recent work has shown that a major population of murine influenza A specific cytotoxic T lymphocytes (CTL) recognize the viral nucleoprotein. In order to investigate the mechanism by which this nonglycoprotein component of the virus is recognized by CTL, a series of deletion mutants of an A virus NP gene were studied. The results showed that CTL recognize three distinct epitopes of the NP molecule. Both N- and C-terminal fragments of the protein are transported, independently of each other, t...Expand abstract
- Publisher copy:
- Copyright date:
Cytotoxic T cells recognize fragments of the influenza nucleoprotein.
If you are the owner of this record, you can report an update to it here: Report update to this record