Journal article icon

Journal article

Methylene blue-mediated hexose monophosphate shunt stimulation in human red blood cells in vitro: independence from intracellular oxidative injury.

Abstract:

The red blood cell hexose monophosphate shunt (HMS) and proteolytic responses to several concentrations of Methylene Blue or sodium nitrite were measured. The results suggested two distinct mechanisms for activation of the HMS: (1) nitrite treatment increased HMS activity in response to oxidative challenge to red cell protein; (2) Methylene Blue treatment activated HMS without injurious oxidative challenge. Nitrite-treated cells actively degraded protein, whereas Methylene Blue-treated red ce...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Journal:
The International journal of biochemistry
Volume:
16
Issue:
10
Pages:
1053-1058
Publication date:
1984
DOI:
ISSN:
0020-711X
URN:
uuid:1f44d91c-5fe2-4074-9217-61933a0b4559
Source identifiers:
81733
Local pid:
pubs:81733

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP