Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism.

Journal article

BACKGROUND: Resistant starch may modulate insulin sensitivity, although the precise mechanism of this action is unknown. OBJECTIVE: We studied the effects of resistant starch on insulin sensitivity and tissue metabolism. DESIGN: We used a 4-wk supplementation period with 30 g resistant starch/d, compared with placebo, in 10 healthy subjects and assessed the results by using arteriovenous difference methods. RESULTS: When assessed by euglycemic-hyperinsulinemic clamp, insulin sensitivity was ...

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Authors: Robertson, MD; Bickerton, A; Dennis, A; Vidal, H; Frayn, K

• Publication status: Published
• Journal: American journal of clinical nutrition
• Volume: 82
• Issue: 3
• Pages: 559-567
• Publication date: 2005-09-01
• EISSN: 1938-3207
• ISSN: 0002-9165
• Language: English
• Keywords: Peptide Hormones; Insulin; Fatty Acids, Volatile; Adult; Adipose Tissue; Muscle, Skeletal; Humans; Gene Expression; Single-Blind Method; Blood Glucose; Postprandial Period; Glucose Clamp Technique; Starch; Cross-Over Studies; Ghrelin; Area Under Curve; Middle Aged; Glucose Tolerance Test; Female; Male; Dietary Carbohydrates; Fatty Acids, Nonesterified