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Journal article

Adaptive deep brain stimulation for movement disorders: the long road to clinical therapy.

Abstract:

Continuous high-frequency DBS is an established treatment for essential tremor and Parkinson's disease. Current developments focus on trying to widen the therapeutic window of DBS. Adaptive DBS (aDBS), where stimulation is dynamically controlled by feedback from biomarkers of pathological brain circuit activity, is one such development. Relevant biomarkers may be central, such as local field potential activity, or peripheral, such as inertial tremor data. Moreover, stimulation may be directed...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/mds.27022

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
More from this funder
Name:
Medical Research Council
Grant:
MC_UU_12024/1
More from this funder
Name:
National Institute for Health Research
Publisher:
Wiley
Journal:
Movement Disorders More from this journal
Volume:
32
Issue:
6
Pages:
810-819
Publication date:
2017-06-08
Acceptance date:
2017-03-19
DOI:
EISSN:
1531-8257
ISSN:
0885-3185
Language:
English
Keywords:
Pubs id:
pubs:700561
UUID:
uuid:1ecd69c0-323d-48e1-a4b1-a204b9ae11c2
Local pid:
pubs:700561
Source identifiers:
700561
Deposit date:
2017-06-29

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