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Journal article

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.

Abstract:

One strategy to restore vision in retinitis pigmentosa and age-related macular degeneration is cell replacement. Typically, patients lose vision when the outer retinal photoreceptor layer is lost, and so the therapeutic goal would be to restore vision at this stage of disease. It is not currently known if a degenerate retina lacking the outer nuclear layer of photoreceptor cells would allow the survival, maturation, and reconnection of replacement photoreceptors, as prior studies used hosts w...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.1119416110

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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
110
Issue:
3
Pages:
1101-1106
Publication date:
2013-01-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
374246
Language:
English
Keywords:
Pubs id:
pubs:374246
UUID:
uuid:1ea6fecf-3809-4d87-8547-586f69eb4a8a
Local pid:
pubs:374246
Deposit date:
2013-11-16

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