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Journal article

Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson's disease.

Abstract:

Alterations of basal ganglia physiology in parkinsonism may consist of two elements, an increase in the firing rate of neurones and a change in the pattern of synchronisation of discharges between neurones. Recent findings suggest the presence of two principal modes of synchronised activity within the human subthalamo-pallidal-thalamo-cortical circuit, at <30 Hz and >60 Hz. These oscillations are dynamically and systematically modulated by task, thereby suggesting a functional role in m...

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Publication status:
Published

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Publisher copy:
10.1002/mds.10358

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
Journal:
Movement disorders : official journal of the Movement Disorder Society
Volume:
18
Issue:
4
Pages:
357-363
Publication date:
2003-04-01
DOI:
EISSN:
1531-8257
ISSN:
0885-3185
Source identifiers:
70856
Language:
English
Keywords:
Pubs id:
pubs:70856
UUID:
uuid:1ea01940-3497-4f74-8418-8c1524bec614
Local pid:
pubs:70856
Deposit date:
2013-02-20

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