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Journal article

Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson's disease.

Abstract:

Alterations of basal ganglia physiology in parkinsonism may consist of two elements, an increase in the firing rate of neurones and a change in the pattern of synchronisation of discharges between neurones. Recent findings suggest the presence of two principal modes of synchronised activity within the human subthalamo-pallidal-thalamo-cortical circuit, at <30 Hz and >60 Hz. These oscillations are dynamically and systematically modulated by task, thereby suggesting a functional role in m...

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Publication status:
Published

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Publisher copy:
10.1002/mds.10358

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Role:
Author
Journal:
Movement disorders : official journal of the Movement Disorder Society
Volume:
18
Issue:
4
Pages:
357-363
Publication date:
2003-04-05
DOI:
EISSN:
1531-8257
ISSN:
0885-3185
URN:
uuid:1ea01940-3497-4f74-8418-8c1524bec614
Source identifiers:
70856
Local pid:
pubs:70856

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