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Pathophysiology of severe falciparum malaria in man.

Abstract:

In humans, severe falciparum malaria disturbs the function of many tissues and organs. It is unlikely that a single pathophysiological process is responsible for the diverse effects of the infection. However, there is increasing evidence that impairment of local blood flow resulting from sticking of parasitized erythrocytes to the venular endothelium may be the initiating cause of cerebral, retinal, renal, gastrointestinal and bone-marrow abnormalities. The harmful effects of malaria are imme...

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Publication status:
Published

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Authors


Warrell, DA More by this author
Journal:
Parasitology
Volume:
94 Suppl
Issue:
SUPPL.
Pages:
S53-S76
Publication date:
1987
EISSN:
1469-8161
ISSN:
0031-1820
URN:
uuid:1e89949d-2c6f-4ea7-a8da-5cff10400bbf
Source identifiers:
61092
Local pid:
pubs:61092

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