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Integrated human-machine interface for closed-loop stimulation using implanted and wearable devices

Abstract:
Recent development in implantable devices for electrical brain stimulation includes sensing and embedded computing capabilities that enable adaptive stimulation strategies. Applications include stimulation triggered by pathologic brain activity and endogenous rhythms, such as circadian rhythms. We developed and tested a system that integrates an electrical brain stimulation & sensing implantable device with embedded computing and uses a distributed system with commercial electronics, smartphone and smartwatch for patient annotations, extensive behavioral testing, and adaptive stimulation in subjects in their natural environments. The system enables precise time synchronization of the external components with the brain stimulating device and is coupled with automated analysis of continuous streaming electrophysiology synchronized with patient reports. The system leverages a real-time bi-directional interface between devices and patients with epilepsy living in their natural environment.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1109/SMC53654.2022.9945203

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Role:
Author
ORCID:
0000-0002-4712-7039
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Role:
Author
ORCID:
0000-0001-9844-7617
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Role:
Author
ORCID:
0000-0002-0693-9495
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Role:
Author
ORCID:
0000-0002-2392-8608


Publisher:
IEEE
Host title:
Proceedings of the IEEE International Conference on Systems, Man, and Cybernetics (SMC 2022)
Pages:
1730-1735
Publication date:
2022-11-18
Event title:
IEEE International Conference on Systems, Man, and Cybernetics (SMC 2022)
Event location:
Prague, Czech Republic
Event website:
https://ieeesmc2022.org/
Event start date:
2022-10-09
Event end date:
2022-10-12
DOI:
EISSN:
2577-1655
ISSN:
1062-922X
ISBN:
9781665452588


Language:
English
Keywords:
Pubs id:
1313732
Local pid:
pubs:1313732
Deposit date:
2023-05-18
ARK identifier:

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