Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?

Journal article

During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged Copyright © 2022 Matthews, Campbell, Sandulescu, Maticic, Ruta, Rivero-Juarez, van Welzen, Tan, Garcia, Gherlan, Cinar, Hasanoglu, Gmizic, Nicolini, Santos, Sargsyants, Velikov, Habibovic, Fourati, Zidovec-Lepej, Herder, Dudman, Miron, Irving and Sahin.https://doi.org/10.3389/fphar.2022.106240

Authors: Matthews, PC; Campbell, C; Săndulescu, O; Matičič, M; Ruta, SM

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Frontiers Media
• Journal: Frontiers in Pharmacology
• Volume: 13
• Pages: 1062408-1062408
• Article number: 1062408
• Publication date: 2022-11-25
• DOI: 10.3389/fphar.2022.1062408
• EISSN: 1663-9812
• ISSN: 1663-9812
• Language: English
• Keywords: Virology; Environmental health; Hepatitis B virus; Epidemiology; Population; HBsAg; Public health; Etiology; Pandemic; Infectious disease (medical specialty); Outbreak; Virus; Disease; Medicine; Coronavirus disease 2019 (COVID-19); Pathology; Immunology