Journal article
Poly ADP-ribose polymerase-1: an international molecule of mystery.
- Abstract:
-
Poly(ADP-ribose) polymerase-1 (PARP-1) is one of the most abundant proteins within mammalian cells. First described more than 45 years ago, PARP-1 has been the subject of many studies and was shown to be involved in multiple aspects of cellular metabolism. Despite many interesting studies that implicate PARP-1 in transcription, chromatin remodelling, apoptosis, DNA repair and several neurological disorders, its precise role is still unclear. This review will discuss the role of PARP-1 in DNA ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.dnarep.2008.03.009
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Bibliographic Details
- Journal:
- DNA repair
- Volume:
- 7
- Issue:
- 7
- Pages:
- 1077-1086
- Publication date:
- 2008-07-01
- DOI:
- EISSN:
-
1568-7856
- ISSN:
-
1568-7864
- Source identifiers:
-
130906
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:130906
- UUID:
-
uuid:1e6c933a-edc5-4cae-b96f-90cae045c8b7
- Local pid:
- pubs:130906
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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