Dopamine denervation of frontal cortex or nucleus accumbens does not affect ACTH-induced grooming behaviour.

Journal article

Studies with dopamine (DA) receptor antagonists have implicated brain DA systems in the increased grooming behaviour elicited by intracerebroventricular (i.c.v.) administration of ACTH or exposure to a novel environment. To evaluate the potential contributions of DA terminals innervating frontal cortex and nucleus accumbens, stereotaxically guided injections of 6-hydroxydopamine (6-OHDA) were made into these regions of rat brain following peripheral administration of desmethylimipramine and p...

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Authors: Dunn, A; Alpert, J; Iversen, S

• Publication status: Published
• Journal: Behavioural brain research
• Volume: 12
• Issue: 3
• Pages: 307-315
• Publication date: 1984-06-01
• DOI: 10.1016/0166-4328(84)90156-6
• EISSN: 1872-7549
• ISSN: 0166-4328
• Language: English
• Keywords: Animals; Dopamine; Rats; Oxidopamine; Adrenocorticotropic Hormone; Norepinephrine; Arousal; Cosyntropin; Motor Activity; Rats, Inbred Strains; Nucleus Accumbens; Receptors, Dopamine; Frontal Lobe; Male; Septal Nuclei; Grooming; Denervation; Hydroxydopamines