Journal article

Valacyclovir for herpes simplex encephalitis.

Abstract:: The recommended treatment for herpes simplex encephalitis (HSE) remains intravenous acyclovir. In resource-poor countries, however, intravenous formulations are usually unavailable or unaffordable. We report the penetration of acyclovir into the cerebrospinal fluid (CSF) in patients with HSE, treated with the oral prodrug valacyclovir at 1,000 mg three times daily. The oral therapy achieved adequate acyclovir concentrations in the CSF and may be an acceptable early treatment for suspected HSE in resource-limited settings.

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Pouplin, T., Pouplin, J., Van Toi, P., Lindegardh, N., Rogier van Doorn, H., Hien, T., Farrar, J., Török, M., & Chau, T. (2011). Valacyclovir for herpes simplex encephalitis. Antimicrobial Agents and Chemotherapy, 55(7), 3624–3626.

MLA Style

Pouplin, T, et al. “Valacyclovir for Herpes Simplex Encephalitis.” Antimicrobial Agents and Chemotherapy, vol. 55, no. 7, 2011, pp. 3624–26.

Chicago Style

Pouplin, T, J Pouplin, P Van Toi, et al. 2011. “Valacyclovir for Herpes Simplex Encephalitis.” Antimicrobial Agents and Chemotherapy 55 (7): 3624–26.
Print

Access Document

Publisher copy:: 10.1128/aac.01023-10

Authors

+ Pouplin, T More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Role:: Author

+ Pouplin, J More by this author

Role:: Author

+ Van Toi, P More by this author

Role:: Author

+ Lindegardh, N More by this author

Role:: Author

+ Rogier van Doorn, H More by this author

Role:: Author

More authors...

Journal:: Antimicrobial agents and chemotherapy More from this journal
Volume:: 55
Issue:: 7
Pages:: 3624-3626
Publication date:: 2011-07-01
DOI:: 10.1128/aac.01023-10
EISSN:: 1098-6596
ISSN:: 0066-4804

Language:: English
Keywords:: Encephalitis, Herpes Simplex

Acyclovir

Valine

Antiviral Agents

Female

Humans

Male
Pubs id:: pubs:140893
UUID:: uuid:1e59adf5-9dd6-4feb-9d02-2424b493e937
Local pid:: pubs:140893
Source identifiers:: 140893
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_1e59adf59dd64feb9d022424b493e937

Terms of use

Copyright date:: 2011

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP