- Abstract:
-
Millions of people receive primaquine against sexual plasmodia responsible for malaria transmission. These gametocytes cause no symptoms and do not threaten the host, but they infect mosquitoes and threaten the community. Primaquine causes hemolysis in the small minority of patients with glucose-6-phosphate dehydrogenase deficiency (G6PDd). Clinical studies in the 1950s demonstrated gametocytocidal primaquine to be safe without G6PDd screening. However, the evaluated G6PDd variant, African A-...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.pt.2010.08.005
-
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- Journal:
- Trends in parasitology
- Volume:
- 27
- Issue:
- 1
- Pages:
- 11-16
- Publication date:
- 2011-01-05
- DOI:
- EISSN:
-
1471-5007
- ISSN:
-
1471-4922
- URN:
-
uuid:1e31d600-e8d8-404f-a803-8a32828d76b4
- Source identifiers:
-
73326
- Local pid:
- pubs:73326
- Copyright date:
- 2011
Journal article
Consideration of ethics in primaquine therapy against malaria transmission.
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