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Journal article

Consideration of ethics in primaquine therapy against malaria transmission.

Abstract:

Millions of people receive primaquine against sexual plasmodia responsible for malaria transmission. These gametocytes cause no symptoms and do not threaten the host, but they infect mosquitoes and threaten the community. Primaquine causes hemolysis in the small minority of patients with glucose-6-phosphate dehydrogenase deficiency (G6PDd). Clinical studies in the 1950s demonstrated gametocytocidal primaquine to be safe without G6PDd screening. However, the evaluated G6PDd variant, African A-...

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Publication status:
Published

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Publisher copy:
10.1016/j.pt.2010.08.005

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
Trends in parasitology
Volume:
27
Issue:
1
Pages:
11-16
Publication date:
2011-01-05
DOI:
EISSN:
1471-5007
ISSN:
1471-4922
URN:
uuid:1e31d600-e8d8-404f-a803-8a32828d76b4
Source identifiers:
73326
Local pid:
pubs:73326

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