Journal article icon

Journal article

Germline BRCA mutation and outcome in young onset breast cancer: POSH, a prospective cohort study

Abstract:

Background: Retrospective studies provide conflicting interpretations of the effect of inherited genetic factors on the prognosis of patients with breast cancer. The primary aim of this study was to determine the effect of a germline BRCA1 or BRCA2 mutation on breast cancer outcomes in patients with young-onset breast cancer.

Methods: We did a prospective cohort study of female patients recruited from 127 hospitals in the UK aged 40 years or younger at first diagnosis (by histologic...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1016/S1470-2045(17)30891-4

Authors


Expand authors...
Wessex Cancer Trust More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Oncology Journal website
Volume:
19
Issue:
2
Pages:
169-180
Publication date:
2018-01-11
Acceptance date:
2017-11-08
DOI:
EISSN:
1474-5488
ISSN:
1474-5488
Source identifiers:
746201
Pubs id:
pubs:746201
UUID:
uuid:1e2a86a5-72ac-4394-8ace-ed38432a3d0d
Local pid:
pubs:746201
Deposit date:
2017-11-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP