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In vitro dendritic cell generation and lymphocyte subsets in myeloma patients: influence of thalidomide and high-dose chemotherapy treatment.

Abstract:

While vaccination with antigen-pulsed dendritic cells (DCs) represents a promising therapeutic strategy in multiple myeloma (MM), clinical benefit, so far, has been limited to individual patients. To identify potential problems with this approach, we have analyzed the influence of treatment parameters, in particular high-dose chemotherapy (HD-CTX) and thalidomide, on in vitro DC generation and peripheral blood lymphocyte subsets in MM patients. From a total of 25 MM patients, including 14 pat...

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Publisher copy:
10.1007/s00262-004-0633-6

Authors


Journal:
Cancer immunology, immunotherapy : CII More from this journal
Volume:
54
Issue:
5
Pages:
506-512
Publication date:
2005-05-01
DOI:
EISSN:
1432-0851
ISSN:
0340-7004
Language:
English
Keywords:
Pubs id:
pubs:260594
UUID:
uuid:1da4d6b2-df43-47bf-b158-6294f8cbcd01
Local pid:
pubs:260594
Source identifiers:
260594
Deposit date:
2012-12-19

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