- Abstract:
-
Background
Altered brain connectivity is implicated in the development and clinical burden of schizophrenia. Relative to matched controls, schizophrenia patients show (1) a global and regional reduction in the integrity of the brain’s white matter (WM), assessed using diffusion tensor imaging (DTI) fractional anisotropy (FA), and (2) accelerated age-related decline in FA values. In the largest mega-analysis to date, we tested if differences in the trajectories of WM tract develop...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 1.1MB)
-
- Publisher copy:
- 10.1002/hbm.23336
-
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- Publisher:
- Wiley Publisher's website
- Journal:
- Human Brain Mapping Journal website
- Volume:
- 37
- Issue:
- 12
- Pages:
- 4673-4688
- Publication date:
- 2016-08-01
- Acceptance date:
- 2016-07-24
- DOI:
- EISSN:
-
1097-0193
- ISSN:
-
1065-9471
- Pubs id:
-
pubs:638225
- URN:
-
uri:1d9671af-5567-443a-b82c-02cbbbbb4ba4
- UUID:
-
uuid:1d9671af-5567-443a-b82c-02cbbbbb4ba4
- Local pid:
- pubs:638225
- Language:
- English
- Keywords:
- Copyright holder:
- Wiley Periodicals, Inc.
- Copyright date:
- 2016
- Notes:
- © 2016 Wiley Periodicals, Inc. This is the accepted manuscript version of the article. The final version is available online from Wiley at: https://doi.org/10.1002/hbm.23336
Journal article
Heterochronicity of white matter development and aging explains regional patient control differences in schizophrenia
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Pfizer
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