Thesis icon

Thesis

Synthetic biology of terpenoid fine chemicals by coupling terpene synthases with engineered P450BM3

Abstract:

Terpenes are a diverse class of natural products biosynthesized by terpene synthases from simple isoprenoid precursors such as farnesyl pyrophosphate (FPP) and geranyl pyrophosphate (GPP). Terpene synthases catalyse the cyclization and rearrangement of these precursors to generate complex hydrocarbon skeletons, which can be further modified by oxidases such as cytochrome P450 enzymes. P450s catalyse the selective oxidation of C−H bonds by inserting an oxygen atom from atmospheric dioxygen ...

Expand abstract

Actions

  • Cite

  • Print

Authors

More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Supervisor
ORCID:
0000-0003-4875-1092

DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Language:
English
Keywords:
Subjects:
Deposit date:
2025-07-14

Terms of use

Views and Downloads





If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP