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Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2.

Abstract:

Recent, primarily structural observations indicate that related viruses, harboring no sequence similarity, infect hosts of different domains of life. One such clade of viruses, defined by common capsid architecture and coat protein fold, is the so-called PRD1-adenovirus lineage. Here we report the structure of the marine lipid-containing bacteriophage PM2 determined by crystallographic analyses of the entire approximately 45 MDa virion and of the outer coat proteins P1 and P2, revealing PM2 t...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Molecular cell More from this journal
Volume:
31
Issue:
5
Pages:
749-761
Publication date:
2008-09-01
DOI:
EISSN:
1097-4164
ISSN:
1097-2765
Language:
English
Keywords:
Pubs id:
pubs:24701
UUID:
uuid:1d8f4704-e01a-4cf2-a059-75167a0001b4
Local pid:
pubs:24701
Source identifiers:
24701
Deposit date:
2012-12-19

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