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Probing multi-scale mechanics of peripheral nerve collagen and myelin by x-ray diffraction

Abstract:

Peripheral nerves are continuously subjected to mechanical forces, both during everyday movement and as a result of traumatic events. Current mechanical models focus on explaining the macroscopic behaviour of the tissue, but do not investigate how tissue strain translates to deformations at the microstructural level. Predicting the effect of macro-scale loading can help explain changes in nerve function and suggest new strategies for prevention and therapy. The aim of this study was to deter...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1016/j.jmbbm.2018.07.030

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Oxford college:
Balliol College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Oxford college:
Wadham College
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Journal of the Mechanical Behavior of Biomedical Materials Journal website
Volume:
87
Issue:
1
Pages:
205-212
Publication date:
2018-07-25
Acceptance date:
2018-07-20
DOI:
EISSN:
1878-0180
ISSN:
1751-6161
Pubs id:
pubs:891700
URN:
uri:1d89cbe2-097b-4441-bd0e-e856dfbce96b
UUID:
uuid:1d89cbe2-097b-4441-bd0e-e856dfbce96b
Local pid:
pubs:891700

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