Journal article icon

Journal article

Remote toehold: A mechanism for flexible control of DNA hybridization kinetics

Abstract:

Hybridization of DNA strands can be used to build molecular devices, and control of the kinetics of DNA hybridization is a crucial element in the design and construction of functional and autonomous devices. Toehold-mediated strand displacement has proved to be a powerful mechanism that allows programmable control of DNA hybridization. So far, attempts to control hybridization kinetics have mainly focused on the length and binding strength of toehold sequences. Here we show that insertion of ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1021/ja1073239
Journal:
Journal of the American Chemical Society More from this journal
Volume:
133
Issue:
7
Pages:
2177-2182
Publication date:
2011-02-23
DOI:
EISSN:
1520-5126
ISSN:
0002-7863
Language:
English
Pubs id:
pubs:161928
UUID:
uuid:1d716fe6-ef0c-459f-b987-3518b1456f84
Local pid:
pubs:161928
Source identifiers:
161928
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP