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Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance

Abstract:

Of the 10 million people estimated to have fallen ill with tuberculosis (TB) in 2019, nearly half million developed TB resistant to rifampicin (RIF), and over one million developed TB susceptible to RIF but resistant to isoniazid (INH). Drug resistance must be detected rapidly and accurately to initiate appropriate and effective treatment.

The detection of RIF resistance has improved significantly in the past decade with the introduction of rapid diagnostic tools based on DNA detec...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Publisher:
World Health Organization Publisher's website
Publication date:
2021-06-25
ISBN:
9789240028173
Language:
English
Keywords:
Pubs id:
1183787
Local pid:
pubs:1183787
Deposit date:
2021-06-28

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