Widened coronary arteries in a feverish child.

Journal article

A 3-year-old girl with fever of unknown origin after a visit to Surinam was seen at our hospital. Signs and symptoms were indicative of either Kawasaki syndrome or an acute viral or (atypical) bacterial illness. No cardiac abnormalities were noted at echocardiography. She was treated with intravenous immunoglobulin and clarithromycin and made a quick recovery. Serologically, the diagnosis of murine typhus was made; a flea-borne rickettsiosis caused by Rickettsia typhi. A follow-up echocardiography 1 week later showed a dilated left coronary artery, which was normal again 4 weeks later. We suggest that this phenomenon was a manifestation of rickettsial vasculitis.

Authors: Van Doorn, H; Lo-A-Njoe, S; Ottenkamp, J; Pajkrt, D

• Publication status: Published
• Journal: Pediatric cardiology
• Volume: 27
• Issue: 4
• Pages: 515-518
• Publication date: 2006-01-01
• DOI: 10.1007/s00246-006-1324-1
• EISSN: 1432-1971
• ISSN: 0172-0643
• Language: English
• Keywords: Child, Preschool; Humans; Anti-Bacterial Agents; Female; Dilatation, Pathologic; Fever; Immunoglobulins, Intravenous; Clarithromycin; Immunologic Factors; Typhus, Endemic Flea-Borne; Treatment Outcome; Coronary Disease