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Journal article

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.

Abstract:

Apc(Min) mice have provided an example of a locus (Modifier of Min1; Mom1) modifying adenoma numbers in the intestines of inbred strains. Linkage analysis located Mom1 on chromosome 4, and further investigation identified secretory phospholipase A2 (Pla2g2a) as a candidate gene. Because of unknown variation introduced by a single founding male mouse, our Min stock, although Pla2g2a(Mom1-s), was not on a pure C57BL/6J background and exhibited several polymorphic loci, including a region on chr...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0500039102

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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
102
Issue:
8
Pages:
2868-2873
Publication date:
2005-02-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
39403
Language:
English
Keywords:
Pubs id:
pubs:39403
UUID:
uuid:1c365a34-ed6f-437d-ae21-6ae05f58ef14
Local pid:
pubs:39403
Deposit date:
2012-12-19

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