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Unravelling the pathogenesis of myasthenia gravis.

Abstract:

Myasthenia gravis is a relatively rare neurological disease that is associated with loss of the acetylcholine receptors that initiate muscle contraction. This results in muscle weakness, which can be life-threatening. The story of how both the physiological basis of the disease and the role of acetylcholine-receptor-specific antibodies were determined is a classic example of the application of basic science to clinical medicine, and it has provided a model for defining other antibody-mediated...

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Publication status:
Published

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Publisher copy:
10.1038/nri916

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Nature reviews. Immunology
Volume:
2
Issue:
10
Pages:
797-804
Publication date:
2002-10-05
DOI:
EISSN:
1474-1741
ISSN:
1474-1733
URN:
uuid:1c1d1da3-2e35-4426-851a-118609ca9240
Source identifiers:
241400
Local pid:
pubs:241400

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