Journal article
Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis.
- Abstract:
-
Interleukin 17 is a T cell-derived cytokine that induces the release of pro-inflammatory mediators in a wide range of cell types. Recently, a subset of IL-17-producing T helper cells (Th17) distinct from Th1 and Th2 cells has been described, which constitutes a new T cell polarization state. Aberrant Th17 responses and overexpression of IL-17 have been implicated in a number of autoimmune disorders including rheumatoid arthritis and multiple sclerosis. Molecules blocking IL-17 such as IL-17-s...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/eji.200636658
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Authors
Bibliographic Details
- Journal:
- European journal of immunology
- Volume:
- 36
- Issue:
- 11
- Pages:
- 2857-2867
- Publication date:
- 2006-11-01
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- Source identifiers:
-
469200
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:469200
- UUID:
-
uuid:1c1ad835-cf39-4d9e-838c-4c11a3bea33c
- Local pid:
- pubs:469200
- Deposit date:
- 2014-06-18
Terms of use
- Copyright date:
- 2006
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