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Journal article

Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis.

Abstract:

Interleukin 17 is a T cell-derived cytokine that induces the release of pro-inflammatory mediators in a wide range of cell types. Recently, a subset of IL-17-producing T helper cells (Th17) distinct from Th1 and Th2 cells has been described, which constitutes a new T cell polarization state. Aberrant Th17 responses and overexpression of IL-17 have been implicated in a number of autoimmune disorders including rheumatoid arthritis and multiple sclerosis. Molecules blocking IL-17 such as IL-17-s...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200636658

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Journal:
European journal of immunology
Volume:
36
Issue:
11
Pages:
2857-2867
Publication date:
2006-11-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Source identifiers:
469200
Language:
English
Keywords:
Pubs id:
pubs:469200
UUID:
uuid:1c1ad835-cf39-4d9e-838c-4c11a3bea33c
Local pid:
pubs:469200
Deposit date:
2014-06-18

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