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THE STABILITY OF DUPLEX DNA CONTAINING 3,N-4-ETHENO-2'-DEOXYCYTIDINE (EPSILON-DC) - A UV MELTING AND HIGH-RESOLUTION H-1-NMR STUDY

Abstract:
The mutagenic lesion 3,N4-etheno-2′-deoxycytidine (εdC) greatly destabilises DNA when paired with each of the natural bases although the solution structure of a duplex containing a εC: A pair shows that the lesion does not greatly disrupt base pairing in the duplex.
Publication status:
Published

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Publisher copy:
10.1039/c39940002241

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS More from this journal
Issue:
19
Pages:
2241-2242
Publication date:
1994-10-07
DOI:
ISSN:
0022-4936
Pubs id:
pubs:400303
UUID:
uuid:1c09466a-9fe5-4bfe-94d9-c113e39dcf92
Local pid:
pubs:400303
Source identifiers:
400303
Deposit date:
2013-11-16

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