Journal article icon

Journal article

Ancient and modern: hints of a core post-transcriptional network driving chemotherapy resistance in ovarian cancer

Abstract:

RNA-binding proteins (RBPs) and noncoding (nc)RNAs (such as microRNAs, long ncRNAs, and others) cooperate within a post-transcriptional network to regulate the expression of genes required for many aspects of cancer behavior including its sensitivity to chemotherapy. Here, using an RBP-centric approach, we explore the current knowledge surrounding contributers to post-transcriptional gene regulation (PTGR) in ovarian cancer and identify commonalities that hint at the existence of an evolution...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/wrna.1432

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Oxford college:
Hertford College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Wiley Interdisciplinary Reviews: RNA Journal website
Volume:
9
Issue:
1
Article number:
e1432
Publication date:
2017-08-01
Acceptance date:
2017-06-12
DOI:
EISSN:
1757-7012
ISSN:
1757-7004
Pmid:
28762650
Language:
English
Pubs id:
pubs:713182
UUID:
uuid:1bfaecb4-7d6c-47bd-bd28-a3b780391ea1
Local pid:
pubs:713182
Deposit date:
2018-01-22

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP