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Journal article

Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics.

Abstract:

Avian influenza A H5N1 viruses similar to those that infected humans in Hong Kong in 1997 continue to circulate in waterfowl and have reemerged in poultry in the region, raising concerns that these viruses could reappear in humans. The currently licensed trivalent inactivated influenza vaccines contain hemagglutinin (HA) and neuraminidase genes from epidemic strains in a background of internal genes derived from the vaccine donor strain, A/Puerto Rico/8/34 (PR8). Such reassortant candidate va...

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Publication status:
Published

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Publisher copy:
10.1006/viro.2002.1742

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Journal:
Virology
Volume:
305
Issue:
1
Pages:
192-200
Publication date:
2003-01-01
DOI:
EISSN:
1096-0341
ISSN:
0042-6822
Source identifiers:
9998
Language:
English
Keywords:
Pubs id:
pubs:9998
UUID:
uuid:1be50150-733c-43ed-90bd-864dabd451a1
Local pid:
pubs:9998
Deposit date:
2012-12-19

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