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Journal article

The role of macrophages in inflammatory bowel diseases.

Abstract:

The small and large intestine contain the largest number of macrophages in the body and these cells are strategically located directly underneath the epithelial layer, enabling them to sample the lumen. Such intestinal macrophages have a different phenotype from other tissue macrophages in that they ingest and may kill microbes but they do not mediate strong pro-inflammatory responses upon microbial recognition. These properties are essential for maintaining a healthy intestine. It is general...

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Publication status:
Published

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Publisher copy:
10.1017/s1462399409001069

Authors


Heinsbroek, SE More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Expert reviews in molecular medicine
Volume:
11
Pages:
e14
Publication date:
2009
DOI:
EISSN:
1462-3994
ISSN:
1462-3994
URN:
uuid:1be45e96-ba8d-4a77-8225-74568031c229
Source identifiers:
53365
Local pid:
pubs:53365

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