Single locus typing of MHC class I and class II B loci in a population of red jungle fowl.

Journal article

In species with duplicated major histocompatibility complex (MHC) genes, estimates of genetic variation often rely on multilocus measures of diversity. It is possible that such measures might not always detect more detailed patterns of selection at individual loci. Here, we describe a method that allows us to investigate classical MHC diversity in red jungle fowl (Gallus gallus), the wild ancestor of the domestic chicken, using a single locus approach. This is possible due to the well-charact...

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Authors: Worley, K; Gillingham, M; Jensen, P; Kennedy, L; Pizzari, T

• Publication status: Published
• Journal: Immunogenetics
• Volume: 60
• Issue: 5
• Pages: 233-247
• Publication date: 2008-05-01
• DOI: 10.1007/s00251-008-0288-0
• EISSN: 1432-1211
• ISSN: 0093-7711
• Language: English
• Keywords: Phylogeny; Genes, MHC Class II; Alleles; Genetic Variation; Species Specificity; Molecular Sequence Data; Animals; Chickens; Evolution, Molecular; Genes, MHC Class I; Amino Acid Sequence