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Persistence of an Occlusion-Negative Recombinant Nucleopolyhedrovirus in Trichoplusia ni Indicates High Multiplicity of Cellular Infection

Abstract:

We use data from the serial passage of co-occluded recombinant Autographa californica nuclear polyhedrosis virus (AcMNPV) to estimate the viral multiplicity of infection of cells within infected insects. Co-occlusion, the incorporation of wild-type and mutant virus genomes in the same occlusion body, has been proposed as a strategy to deliver genetically modified viruses as insecticides in a way that contains their spread in the environment. It may also serve as a means whereby naturally occu...

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
Journal:
Applied and Environmental Microbiology
Volume:
67
Issue:
3-12
Pages:
5204-5209
Publication date:
2001-01-01
ISSN:
0099-2240
Language:
English
Pubs id:
pubs:210808
UUID:
uuid:1bd7835e-630f-4de0-be07-3bd02cf57b99
Local pid:
pubs:210808
Source identifiers:
210808
Deposit date:
2013-11-16

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