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Journal article

Variants of the chemokine receptor CCR5 are associated with severe bronchiolitis caused by respiratory syncytial virus.

Abstract:

Respiratory syncytial virus (RSV) bronchiolitis is characterized by intense inflammation of the airways, and high levels of proinflammatory cytokines and chemokines can be found in respiratory secretions of affected infants. Important among these chemokines are RANTES (regulated on activation, normal T cell-expressed and -secreted) and macrophage inflammatory-protein alpha, MIP-1alpha, both of which show correlation with severe RSV bronchiolitis. It is not clear whether high levels of these c...

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Publication status:
Published

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Publisher copy:
10.1086/377587

Authors


Rowlands, K More by this author
Lockhart, E More by this author
Sharland, M More by this author
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Journal:
The Journal of infectious diseases
Volume:
188
Issue:
6
Pages:
904-907
Publication date:
2003-09-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:1bd4744e-8014-473c-9cc8-46cccd89d199
Source identifiers:
133521
Local pid:
pubs:133521

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