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The crystal structure of the Hazara virus nucleocapsid protein

Abstract:

Background Hazara virus (HAZV) is a member of the Bunyaviridae family of segmented negative stranded RNA viruses, and shares the same serogroup as Crimean-Congo haemorrhagic fever virus (CCHFV). CCHFV is responsible for fatal human disease with a mortality rate approaching 30 %, which has an increased recent incidence within southern Europe. There are no preventative or therapeutic treatments for CCHFV-mediated disease, and thus CCHFV is classified as a hazard group 4 pathogen. In contrast HA...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12900-015-0051-3

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
BioMed Central
Journal:
BMC Structural Biology More from this journal
Volume:
15
Issue:
1
Pages:
24
Publication date:
2015-12-29
Acceptance date:
2015-12-23
DOI:
EISSN:
1472-6807
Language:
English
Keywords:
Pubs id:
pubs:659774
UUID:
uuid:1bc8878f-7171-4078-8487-6add6e4cce42
Local pid:
pubs:659774
Source identifiers:
659774
Deposit date:
2016-12-13

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