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Population genetics of the HL-A system. A summary of data from the Fifth International Histocompatibility Testing Workshop.

Abstract:

The HL A system is an antigenic polymorphism detectable on most human tissues except erythrocytes. At present two loci, LA and 4 have been identified. They have about 14 and 17 alleles respectively and are separated by a recombination fraction of 0.8%. The high level of polymorphism, reflected in the low frequency of homozygosity observed in the HL A system, about 13% in Europeans compared with 58% for the mean of ABO, MN, Rh, Fy and K, allows the system to contribute as much information to p...

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Journal:
Israel journal of medical sciences More from this journal
Volume:
9
Issue:
9
Pages:
1257-1268
Publication date:
1973-01-01
ISSN:
0021-2180

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