A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression

Badat, M; Davies, JOJ; Fisher, CA; Downes, DJ; Rose, A; Glenthøj, AB; van Beers, EJ; Harteveld, CL; Higgs, DR

Journal article : Letter

A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression

Publication status:: Published

Peer review status:: Reviewed (other)

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APA Style

Badat, M., Davies, J. O. J., Fisher, C. A., Downes, D. J., Rose, A., Glenthøj, A. B., van Beers, E. J., Harteveld, C. L., & Higgs, D. R. (2021). A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression. Blood, 137(4), 572–575.

MLA Style

Badat, M., et al. “A Remarkable Case of HbH Disease Illustrates the Relative Contributions of the α-Globin Enhancers to Gene Expression.” Blood, vol. 137, no. 4, American Society of Hematology, 2021, pp. 572–75.

Chicago Style

Badat, M, JOJ Davies, CA Fisher, DJ Downes, A Rose, AB Glenthøj, EJ van Beers, CL Harteveld, and DR Higgs. 2021. “A Remarkable Case of HbH Disease Illustrates the Relative Contributions of the α-Globin Enhancers to Gene Expression.” Blood 137 (4): 572–75.
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Files:: Badat_et_al_2021_Erratum.pdf

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Publisher copy:: 10.1182/blood.2020006680

Authors

+ Badat, M More by this author

Institution:

University of Oxford

Division:

MSD

Department:

RDM

Sub department:

Weatherall Insti. of Molecular Medicine

Role:

Author

+ Davies, JOJ More by this author

Institution:

University of Oxford

Division:

MSD

Department:

RDM

Sub department:

RDM Clinical Laboratory Sciences

Role:

Author

ORCID:

0000-0002-4108-4357

+ Fisher, CA More by this author

Institution:

University of Oxford

Division:

MSD

Department:

RDM

Sub department:

Weatherall Insti. of Molecular Medicine

Role:

Author

+ Downes, DJ More by this author

Institution:

University of Oxford

Division:

MSD

Department:

RDM

Sub department:

RDM Clinical Laboratory Sciences

Oxford college:

All Souls College

Role:

Author

ORCID:

0000-0002-5034-0869

+ Rose, A More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Paediatrics

Role:

Author

ORCID:

0000-0001-9737-6925

More authors...

Funding

+ Medical Research Council More from this funder

Grant:

MR/T014067/1

MC_EX_MR/R023301/1

MR/R008108/1

MC_PC_14131

MC_PC_15069

MR/K01577X/1

G1000801

G0902418

+ National Institute for Health Research More from this funder

Grant:

ACF-2016-13-003

CL-2018-13-005

+ Wellcome Trust More from this funder

Grant:

106130/Z/14/Z

Bibliographic Details

Publisher:: American Society of Hematology
Journal:: Blood More from this journal
Volume:: 137
Issue:: 4
Pages:: 572-575
Publication date:: 2021-01-28
Acceptance date:: 2020-10-02
DOI:: 10.1182/blood.2020006680
EISSN:: 1528-0020
ISSN:: 0006-4971
Pmid:: 33113553

Item Description

Language:: English
Keywords:: pair 16

beta-Globins

genotype

Human

Alleles

Chromatin

Gene Deletion

Enhancer Elements

alpha-Thalassemia

Pedigree

gene expression regulation

Hemoglobin H

RNA

Male

messenger

alpha-globins

hemoglobin E

erythroblasts

genetic

chromosomes

Sequence Deletion

Suriname

erythropoiesis
Subtype:: Letter
Pubs id:: 1140143
Local pid:: pubs:1140143
Deposit date:: 2023-11-15

Terms of use

Copyright holder:: The American Society of Hematology

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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Journal article : Letter

A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression

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