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A cell cycle model for somitogenesis: mathematical formulation and numerical simulation

Abstract:

After many years of research, the mechanisms that generate a periodic pattern of repeated elements (somites) along the length of the embryonic body axis is still one of the major unresolved problems in developmental biology. Here we present a mathematical formulation of the cell cycle model for somitogenesis proposed in Development105 (1989), 119–130. Somite precursor cells in the node are asynchronous, and therefore, as a population, generate continuously pre-somite cells which enter the seg...

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J. R. Collier More by this author
D. McInerney More by this author
S. Schnell More by this author
P. K. Maini More by this author
D. J. Gavaghan More by this author
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Publication date:
2000
URN:
uuid:1bb68cef-3332-4bb8-8f90-6b534ecb2019
Local pid:
oai:eprints.maths.ox.ac.uk:409

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