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Analysis of quantitative trait loci that influence animal behavior.

Abstract:

Behavioral differences between inbred strains of mice and rats have a genetic basis that can now be dissected using quantitative trait locus (QTL) analysis. Over the last 10 years, a large number of genetic loci that influence behavior have been mapped. In this article I review what that information has revealed about the genetic architecture of behavior. I show that most behaviors are influenced by QTL of small effect, each contributing to less than 10% of the variance of a behavioral trait....

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Publication status:
Published

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Publisher copy:
10.1002/neu.10161

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Journal of neurobiology
Volume:
54
Issue:
1
Pages:
46-77
Publication date:
2003-01-01
DOI:
EISSN:
1097-4695
ISSN:
0022-3034
Source identifiers:
32276

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