Journal article icon

Journal article

Parathyroid hormone-related protein is induced by hypoxia and promotes expression of the differentiated phenotype of human articular chondrocytes.

Abstract:

PTHrP (parathyroid hormone-related protein) is crucial for normal cartilage development and long bone growth and acts to delay chondrocyte hypertrophy and terminal differentiation in the growth plate. After growth plate closure adult HACs (human articular chondrocytes) still produce PTHrP, suggesting a possible role for this factor in the permanent articular cartilage. However, the expression regulation and function of PTHrP in the permanent articular cartilage is unknown. Human articular car...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1042/cs20120610

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Clinical science (London, England : 1979)
Volume:
125
Issue:
10
Pages:
461-470
Publication date:
2013-11-01
DOI:
EISSN:
1470-8736
ISSN:
0143-5221
Source identifiers:
417471

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP