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A sibling-pair based approach for mapping genetic loci that influence quantitative measures of reading disability.

Abstract:

Family and twin studies consistently demonstrate a significant role for genetic factors in the aetiology of the reading disorder dyslexia. However, dyslexia is complex at both the genetic and phenotypic levels, and currently the nature of the core deficit or deficits remains uncertain. Traditional approaches for mapping disease genes, originally developed for single-gene disorders, have limited success when there is not a simple relationship between genotype and phenotype. Recent advances in ...

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Publication status:
Published

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Publisher copy:
10.1054/plef.2000.0187

Authors


Francks, C More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Marlow, AJ More by this author
Richardson, AJ More by this author
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Journal:
Prostaglandins, leukotrienes, and essential fatty acids
Volume:
63
Issue:
1-2
Pages:
27-31
Publication date:
2000
DOI:
EISSN:
1532-2823
ISSN:
0952-3278
URN:
uuid:1ba6c2a5-f504-4200-9c0a-f1916825c36f
Source identifiers:
31744
Local pid:
pubs:31744

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