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A sibling-pair based approach for mapping genetic loci that influence quantitative measures of reading disability.

Abstract:

Family and twin studies consistently demonstrate a significant role for genetic factors in the aetiology of the reading disorder dyslexia. However, dyslexia is complex at both the genetic and phenotypic levels, and currently the nature of the core deficit or deficits remains uncertain. Traditional approaches for mapping disease genes, originally developed for single-gene disorders, have limited success when there is not a simple relationship between genotype and phenotype. Recent advances in ...

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Publication status:
Published

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Publisher copy:
10.1054/plef.2000.0187

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
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Journal:
Prostaglandins, leukotrienes, and essential fatty acids
Volume:
63
Issue:
1-2
Pages:
27-31
Publication date:
2000-01-01
DOI:
EISSN:
1532-2823
ISSN:
0952-3278
Source identifiers:
31744
Language:
English
Keywords:
Pubs id:
pubs:31744
UUID:
uuid:1ba6c2a5-f504-4200-9c0a-f1916825c36f
Local pid:
pubs:31744
Deposit date:
2012-12-19

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