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Ageladine A: an antiangiogenic matrixmetalloproteinase inhibitor from the marine sponge Agelas nakamurai.

Abstract:
A novel MMP inhibitor, ageladine A (1) with antiangiogenic activity was isolated from a marine sponge Agelas nakamurai. Structure 1 was determined by a combination of spectroscopic and chemical methods to be an unprecedented structure of 4-(4,5-dibromo-1H-pyrrol-2-yl)]-1H-imidazo[4,5-c]pyridin-2-amine.

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Publisher copy:
10.1021/ja038025w

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Journal:
Journal of the American Chemical Society
Volume:
125
Issue:
51
Pages:
15700-15701
Publication date:
2003-12-01
DOI:
EISSN:
1520-5126
ISSN:
0002-7863
Source identifiers:
224068
Language:
English
Keywords:
Pubs id:
pubs:224068
UUID:
uuid:1ba0cf3d-2101-47e9-af0c-d27160638a22
Local pid:
pubs:224068
Deposit date:
2012-12-19

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