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Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia.

Abstract:

Schizophrenia is a major neuropsychiatric disorder that affects 2% of the population worldwide. No biochemical diagnostic tests are available, and patients must undergo lengthy clinical evaluation periods before an accurate diagnosis can be given. Blood and cerebrospinal fluid are candidates for the identification of potential biomarkers for this disease. We have identified several N-glycans that distinguish first onset, unmedicated schizophrenia patients from healthy individuals. This is the...

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Publisher copy:
10.1021/pr1002356

Authors


Stanta, JL More by this author
Saldova, R More by this author
Struwe, WB More by this author
Leweke, FM More by this author
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Journal:
Journal of proteome research
Volume:
9
Issue:
9
Pages:
4476-4489
Publication date:
2010-09-05
DOI:
EISSN:
1535-3907
ISSN:
1535-3893
URN:
uuid:1b9e8f33-3d03-42ee-b4d3-097fd907b7b8
Source identifiers:
222842
Local pid:
pubs:222842

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