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Journal article

Pharmaceutical development and optimization of azithromycin suppository for paediatric use.

Abstract:

Pharmaceutical development and manufacturing process optimization work was undertaken in order to propose a potential paediatric rectal formulation of azithromycin as an alternative to existing oral or injectable formulations. The target product profile was to be easy-to-use, cheap and stable in tropical conditions, with bioavailability comparable to oral forms, rapidly achieving and maintaining bactericidal concentrations. PEG solid solution suppositories were characterized in vitro using vi...

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Publication status:
Published

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Journal:
International journal of pharmaceutics
Volume:
441
Issue:
1-2
Pages:
218-226
Publication date:
2013-01-05
DOI:
EISSN:
1873-3476
ISSN:
0378-5173
URN:
uuid:1b9be1fa-0a90-430e-ba53-7a3795d8550b
Source identifiers:
367647
Local pid:
pubs:367647

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