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Transcribed dark matter: meaning or myth?

Abstract:

Genomic tiling arrays, cDNA sequencing and, more recently, RNA-Seq have provided initial insights into the extent and depth of transcribed sequence across human and other genomes. These methods have led to greatly improved annotations of protein-coding genes, but have also identified transcription outside of annotated exons. One resultant issue that has aroused dispute is the balance of transcription of known exons against transcription outside of known exons. While non-genic 'dark matter' tr...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddq362

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Human molecular genetics
Volume:
19
Issue:
R2
Pages:
R162-R168
Publication date:
2010-10-01
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
Source identifiers:
239467
Language:
English
Keywords:
Pubs id:
pubs:239467
UUID:
uuid:1b88815f-23a6-45c8-a4c8-2b86d790e374
Local pid:
pubs:239467
Deposit date:
2012-12-19

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