Journal article icon

Journal article

The pelvis-kidney junction contains HCN3, a hyperpolarization-activated cation channel that triggers ureter peristalsis.

Abstract:

Peristaltic waves of the ureteric smooth muscles move urine down from the kidney, a process that is commonly defective in congenital diseases. To study the mechanisms that control the initiation and direction of contractions, we used video microscopy and optical mapping techniques and found that electrical and contractile waves began in a region where the renal pelvis joined the connective tissue core of the kidney. Separation of this pelvis-kidney junction from more distal urinary tract segm...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/ki.2009.483

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics, BHF Centre of Research Excellence
Role:
Author
Journal:
Kidney international
Volume:
77
Issue:
6
Pages:
500-508
Publication date:
2010-03-05
DOI:
EISSN:
1523-1755
ISSN:
0085-2538
URN:
uuid:1b8747b9-3762-4a2c-8113-dad785c98c76
Source identifiers:
164460
Local pid:
pubs:164460

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP