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Journal article

Simulations of ion channels--watching ions and water move.

Abstract:

Ion channels mediate electrical excitability in neurons and muscle. Three-dimensional structures for model peptide channels and for a potassium (K+) channel have been combined with computer simulations to permit rigorous exploration of structure-function relations of channels. Water molecules and ions within transbilayer pores tend to diffuse more slowly than in bulk solutions. In the narrow selectivity filter of the bacterial K+ channel (i.e. the region of the channel that discriminates betw...

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Publication status:
Published

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Journal:
Trends in biochemical sciences More from this journal
Volume:
25
Issue:
8
Pages:
368-374
Publication date:
2000-08-01
DOI:
ISSN:
0968-0004
Language:
English
Keywords:
Pubs id:
pubs:100472
UUID:
uuid:1b872182-8264-4102-875c-197530546c5f
Local pid:
pubs:100472
Source identifiers:
100472
Deposit date:
2012-12-19

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