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Journal article

Sparse but selective and potent synaptic transmission from the globus pallidus to the subthalamic nucleus.

Abstract:

The reciprocally connected GABAergic globus pallidus (GP)-glutamatergic subthalamic nucleus (STN) network is critical for voluntary movement and an important site of dysfunction in movement disorders such as Parkinson's disease. Although the GP is a key determinant of STN activity, correlated GP-STN activity is rare under normal conditions. Here we define fundamental features of the GP-STN connection that contribute to poorly correlated GP-STN activity. Juxtacellular labeling of single GP neu...

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Publication status:
Published

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Publisher copy:
10.1152/jn.00305.2009

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Sub department:
BNDU
Role:
Author
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Journal:
Journal of neurophysiology
Volume:
102
Issue:
1
Pages:
532-545
Publication date:
2009-07-01
DOI:
EISSN:
1522-1598
ISSN:
0022-3077
Source identifiers:
330495

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