Moods, misattributions and mania: an interaction of biological and psychological factors in the pathogenesis of mania.

Journal article

Circadian rhythm dysfunction has recently been suggested to have a causal role in major depressive disorders. Against this background, experiments on circadian rhythms are outlined that yield a state of sustained sleepless activity. Such states can be brought about it seems by manipulation of the external zeitgebers to which rhythms are synchronized rather than by any alteration of the circadian clock. This can be expected to yield a disorganized rhythmic state rather than any discrete phase ...

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Authors: Healy, D; Williams, J

• Publication status: Published
• Journal: Psychiatric developments
• Volume: 7
• Issue: 1
• Pages: 49-70
• Publication date: 1989-01-01
• ISSN: 0262-9283
• Language: English
• Keywords: Bipolar Disorder; Receptors, Neurotransmitter; Circadian Rhythm; Cognition; Psychotropic Drugs; Humans; Cognitive Therapy