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Efficacy of artesunate-mefloquine for chloroquine-resistant Plasmodium vivax malaria in Malaysia: An open-label, randomized, controlled trial.

Abstract:

Background

Chloroquine (CQ)-resistant Plasmodium vivaxis increasingly reported throughout southeast Asia. The efficacy of CQ and alternative artemisinin combination therapies (ACTs) for vivax malaria in Malaysia is unknown.

Methods

A randomized, controlled trial of CQ vs artesunate-mefloquine (AS-MQ) for uncomplicated vivax malaria was conducted in 3 district hospitals in Sabah, Malaysia. Primaquine was administered on day 28. The primary outcome was the cumulative...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/cid/ciw121

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Funding agency for:
Price, RN
Publisher:
Oxford University Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Pages:
ciw121
Publication date:
2016-04-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:1b72d3ef-9452-4b27-a46f-eee49cc5f62e
Source identifiers:
619916
Local pid:
pubs:619916

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