A common biological basis of obesity and nicotine addiction.

Journal article

Smoking influences body weight such that smokers weigh less than non-smokers and smoking cessation often leads to weight increase. The relationship between body weight and smoking is partly explained by the effect of nicotine on appetite and metabolism. However, the brain reward system is involved in the control of the intake of both food and tobacco. We evaluated the effect of single-nucleotide polymorphisms (SNPs) affecting body mass index (BMI) on smoking behavior, and tested the 32 SNPs i...

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Authors: Thorgeirsson, T; Gudbjartsson, D; Sulem, P; Besenbacher, S; Styrkarsdottir, U

• Publication status: Published
• Journal: Translational psychiatry
• Volume: 3
• Issue: 10
• Pages: e308
• Publication date: 2013-01-01
• DOI: 10.1038/tp.2013.81
• EISSN: 2158-3188
• ISSN: 2158-3188
• Language: English
• Keywords: TAG Consortium; Humans; Iceland; Smoking; ENGAGE consortium; Polymorphism, Single Nucleotide; Oxford-GSK Consortium; Obesity; Behavior, Addictive; Age of Onset; Tobacco Use Disorder; Body Mass Index