Journal article
Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease.
- Abstract:
-
Alzheimer's disease (AD) is characterized by a complex neurodegenerative process affecting multiple genes and proteins in the neocortex, many of which have not been well-studied. In this study, we investigated genome-wide gene alterations in the temporal cortex of a well-characterized cohort of AD patients using a recently developed microarray platform, and compared some of the transcript changes with immunoblotting. Of the 5485 genes found to be significantly altered in AD, there were consis...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/jnr.22290
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Authors
Bibliographic Details
- Journal:
- Journal of neuroscience research
- Volume:
- 88
- Issue:
- 6
- Pages:
- 1157-1169
- Publication date:
- 2010-05-05
- DOI:
- EISSN:
-
1097-4547
- ISSN:
-
0360-4012
- URN:
-
uuid:1b63b6dc-9cfe-4cb3-b5a4-4e6b022f3b84
- Source identifiers:
-
195512
- Local pid:
- pubs:195512
Item Description
Terms of use
- Copyright date:
- 2010
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